After some research, I'm guessing that you are talking about:
"Dimethyltryptamine (DMT, aka "The Spirit Molecule"), a molecule found throughout nature, within humans, and potentially existing in every living organism. A compound that commonly produces mystical states"
I know nothing more about it than what I found by googling it. I think anything that puts us into a position of not being in control should be avoided, other than allowing the Holy Spirit to be in control that is.
Evil spirits? I don't know, but it does seem as though by taking this drug, it would open a person up to that.
What does it do to your body? This is what I found:
"Dimethyltryptamine dose slightly elevated blood pressure, heart rate, pupil diameter, and rectal temperature, in addition to elevating blood concentrations of beta-endorphin, corticotropin, cortisol, and prolactin. Growth hormone blood levels rose equally in response to all doses of DMT, and melatonin levels were unaffected. ... Psychologically, the DMT experience can be overly-intense, potentially causing overwhelming fear and difficulty integrating experiences ..." ~Wikipedia
"When the chemical enters the brain, it interferes with the normally occurring neurotransmitter called serotonin. Serotonin serves many functions in the brain, from regulating moods to assisting the brain in the way it processes information. ... serotonin plays a role in how people sense reality" ~
Drug Substance Encyclopedia
Not something be messing around with.
What does God say about this ... Ephesians 5; Galatians 5; Romans 8 would be good chapters to read.
Christ says: "Remain in Me, and I will remain in you. No branch can bear fruit by itself; it must remain in the vine. Neither can you bear fruit unless you remain in Me" (John 15:4-5).
If something else is in control - then we are not remaining in Him.